(±)-α-Tocoferol

synthetic, ≥96% (HPLC)

Sinônimo(s):

DL-all-rac-α-Tocoferol, Vitamina E

Sobre este item

Fórmula empírica (Notação de Hill):

C₂₉H₅₀O₂

CAS Number:

10191-41-0

Peso molecular:

430.71

Beilstein:

94012

Número CE:

233-466-0

Número MDL:

MFCD00006848

Código UNSPSC:

12352205

eCl@ss:

34058016

ID de substância PubChem:

24900118

NACRES:

NA.77

fonte biológica

synthetic

Nível de qualidade

200

Ensaio

≥96% (HPLC)

Formulário

liquid

técnica(s)

HPLC: suitable

cor

faint brown to brown
yellow to very dark yellow

solubilidade

H₂O: insoluble
acetone: miscible
chloroform: miscible
ethanol: miscible
vegetable oils: miscible

densidade

0.950 g/mL at 20 °C (lit.)

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

CC(C)CCCC(C)CCCC(C)CCCC1(C)CCc2c(C)c(O)c(C)c(C)c2O1

InChI

1S/C29H50O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h20-22,30H,9-19H2,1-8H3

chave InChI

GVJHHUAWPYXKBD-UHFFFAOYSA-N

Aplicação

(±)-α-Tocopherol has been used for preparing mycobacterial emulsions. It has also been used to study its immunomodulatory effect on influenza virus.

Ações bioquímicas/fisiológicas

Tocopherols (vitamin E) comprise of a series (α, β, γ and δ) of chiral compounds that differ by the methylation degree of the phenol moiety of the chromanol ring. They function as lipid soluble antioxidants and protect cell membranes from oxidative damage. α-tocopherols are favorably absorbed by humans and their nicotinate salts can function as vitamin E supplements. Studies have also reported that vitamin E can prevent cell damage caused by pharmacologically induced epilepsy in rats.

Nota de preparo

(±)-α-Tocopherol is miscible with chloroform, ethanol, ether, acetone, and vegetable oils. However, it is practically insoluble in water. (±)-α-Tocopherol is unstable under alkaline conditions.