Taurocolato De Sódio Hidratado (Sodium Taurocholate Hydrate) - 1 Gr - Sigma
Código: 17055
Sodium taurocholate hydrate
≥97.0% (TLC)
Synonym: Taurocholic acid sodium salt
- CAS Number 345909-26-4
- Empirical Formula (Hill Notation) C26H44NNaO7S · xH2O
- Molecular Weight 537.68 (anhydrous basis)
- Beilstein/REAXYS Number 3901620
- EC Number 205-653-7
- MDL number MFCD00150819
- PubChem Substance ID 57653098
- NACRES NA.77
Propriedades
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Related Categories |
Anionic Detergents, Bile Salts, Bile acids and Derivatives, Biochemicals and Reagents, Cell Culture, Mais... |
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Quality Level |
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biological source |
ox bile |
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|
synthetic |
|
description |
anionic |
|
assay |
≥97.0% (TLC) |
|
form |
powder |
|
optical activity |
[α]20/D +23±1°, c = 3% in H2O (dry matter) |
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mol wt |
537.68 g/mol (anhydrous basis) |
|
impurities |
≤1% taurine |
|
|
≤2% cholic acid |
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solubility |
H2O: 50 mg/mL, clear |
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functional group |
sulfonic acid |
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storage temp. |
room temp |
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SMILES string |
O.[Na+].C[C@H](CCC(=O)NCCS([O-])(=O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C |
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InChI |
1S/C26H45NO7S.Na.H2O/c1-15(4-7-23(31)27-10-11-35(32,33)34)18-5-6-19-24-20(14-22(30)26(18,19)3)25(2)9-8-17(28)12-16(25)13-21(24)29;;/h15-22,24,28-30H,4-14H2,1-3H3,(H,27,31)(H,32,33,34);;1H2/q;+1;/p-1/t15-,16+,17-,18-,19+,20+,21-,22+,24+,25+,26-;;/m1../s1 |
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InChI key |
RDAJAQDLEFHVNR-NEMAEHQESA-M |
Descrição
Application
Sodium taurocholate hydrate was used as an emulsifier in in situ preparation of digestive enzymes.[4]
Biochem/physiol Actions
Taurocholic acid is the main end product of cholesterol catabolism. During enterohepatic circulation, bile taurocholic acid is converted by the microorganisms to taurodeoxycholic acid and deoxycholic acid.[3] These are reabsorbed by the liver via a carrier-mediated process and converted by liver enzymes to taurocholic acid.[3][1]
Preparation Note
Sodium taurocholate hydrate yields a clear, colorless solution in water at 50 mg/ml.
Other Notes
For the solubilization of unconjugated bilirubin
