N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride

purum, ≥98.0% (AT)

Sinônimo(s):

EDC, WSC hydrochloride, N-Ethyl-N′-(3-dimethylaminopropyl)carbodiimide hydrochloride, EDAC, EDC hydrochloride

Empirical Formula (Hill Notation):

C₈H₁₇N₃ · HCl

Número CAS:

25952-53-8

Peso molecular:

191.70

Beilstein:

5764110

Beilstein:

1718733

Número EC:

200-578-6

Número EC:

247-361-2

Número MDL:

MFCD00012503

Número MDL:

MFCD00003568

ID de substância PubChem:

24845403

ID de substância PubChem:

329747708

NACRES:

NA.31

Nível de qualidade

200

densidade de vapor

1.59 (vs air)

grau

purum

pressão de vapor

44.6 mmHg ( 20 °C)

teor

≥98.0% (AT)
≥99.8% (based on denaturant-free substance)

temperatura de autoignição

683 °F

pf

110-115 °C (lit.)
110-115 °C
−114 °C (lit.)

qualidade

absolute alcohol, denaturated with 1% diethyl phthalate, A15 DEP¹

Lim. expl.

19 %, 60 °F

solubilidade

H₂O: soluble 1 gm/10 ml, clear to very slightly hazy, colorless to very faintly yellow

temperatura de armazenamento

−20°C

índice de refração

n20/D 1.3600 (lit.)
n20/D 1.363

pb

78 °C (lit.)

densidade

0.789 g/mL at 25 °C (lit.)

SMILES string

CCO
Cl.CCN=C=NCCCN(C)C

InChI

1S/C2H6O/c1-2-3/h3H,2H2,1H3
1S/C8H17N3.ClH/c1-4-9-8-10-6-5-7-11(2)3;/h4-7H2,1-3H3;1H

InChI key

LFQSCWFLJHTTHZ-UHFFFAOYSA-N
FPQQSJJWHUJYPU-UHFFFAOYSA-N

Aplicação

N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride has been used modify the cell surface of Escherichia coli to covalently couple substances. It has also been used as an activator to modify microfluidic chips to capture Escherichia coli.

Ações bioquímicas/fisiológicas

N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide is a water soluble condensing reagent. EDAC is generally utilized as a carboxyl activating agent for amide bonding with primary amines. Additionally, it reacts with phosphate groups. It has been utilized in peptide synthesis, crosslinking proteins to nucleic acids as well as preparation of immunoconjugates.

Water soluble condensing reagent. EDAC is generally utilized as a carboxyl activating agent for amide bonding with primary amines. In addition, it will react with phosphate groups. EDAC has been used in peptide synthesis; crosslinking proteins to nucleic acids; and preparation of immunoconjugates as examples. Typically, EDAC is utilized in the pH range 4.0-6.0 without buffers. In particular, amine and carboxylate buffers should be avoided.

Outras notas

Sales restrictions may apply

Nota de rodapé

¹Distribution and use of ethyl alcohol in Switzerland require a license from the Swiss Federal Alcohol Administration

Informações legais

Honeywell is a registered trademark of Honeywell International Inc.