MEROPENEM TRIHYDRATE >=98% (HPLC) – 10 MG - SIGMA

Sinônimo(s):

(1R,5S,6S)-2-[(3S,5S)-5-(dimethylaminocarbonyl)pyrrolidin-3-ylthio]-6-[(R)-1-hydroxyethyl]-1-methylcarbapen-2-em-3-carboxylic acid trihydrate

Empirical Formula (Hill Notation):

C₁₇H₂₅N₃O₅S · 3H₂O

Número CAS:

119478-56-7

Peso molecular:

437.51

Número MDL:

MFCD08600005

NACRES:

NA.77

Nível de qualidade

100

teor

≥98% (HPLC)

forma

powder

condição de armazenamento

desiccated

cor

white to off-white

solubilidade

DMSO: ≥20 mg/mL

originador

AstraZeneca

temperatura de armazenamento

−20°C

SMILES string

O.O.O.C[C@@H](O)[C@@H]1[C@H]2[C@@H](C)C(S[C@@H]3CN[C@@H](C3)C(=O)N(C)C)=C(N2C1=O)C(O)=O

InChI

1S/C17H25N3O5S.3H2O/c1-7-12-11(8(2)21)16(23)20(12)13(17(24)25)14(7)26-9-5-10(18-6-9)15(22)19(3)4;;;/h7-12,18,21H,5-6H2,1-4H3,(H,24,25);3*1H2/t7-,8-,9+,10+,11-,12-;;;/m1.../s1

InChI key

CTUAQTBUVLKNDJ-OBZXMJSBSA-N

Descrição geral

Meropenem trihydrate (MRP) belongs to the carbapenem group of compounds. It is susceptible to degradation at high temperature and humidity.[1] It is soluble in methanol-water or acetone-water combinations. It is used as an antibacterial agent for treating meningitis and pneumonia.[2]

Aplicação

Meropenem trihydrate has been used in the

antibiotic susceptibility testing of E coli isolates from harbor estuary sediment samples[3]

in the bacterial killing assay and for screening antibiotic resistance of cystic fibrosis patient′s sputum based Staphylococcus aureus transformed macrophages in phagocyte infection[4]

for screening Enterococcus faecalis from human bile[5]

Embalagem

10, 50 mg in glass bottle

Ações bioquímicas/fisiológicas

Meropenem trihydrate is an ultra-broad spectrum beta-lactam antibiotic active against both Gram-positive and Gram-negative bacteria.