P-Toluenesulfonyl Chloride ReagentPlus^®, ≥99%

Sinônimo(s):

TsCl, Tosyl chloride

Fórmula linear:

CH₃C₆H₄SO₂Cl

Número CAS:

98-59-9

Peso molecular:

190.65

Beilstein:

607898

Número EC:

202-684-8

Número MDL:

MFCD00007450

ID de substância PubChem:

57648053

NACRES:

NA.21

pressão de vapor

1 mmHg ( 88 °C)

Nível de qualidade

200

linha de produto

ReagentPlus^®

Ensaio

≥99%

forma

solid

pb

134 °C/10 mmHg (lit.)

pf

65-69 °C (lit.)

solubilidade

benzene: freely soluble(lit.)
chloroform: freely soluble(lit.)
ethanol: freely soluble(lit.)
water: insoluble(lit.)

SMILES string

Cc1ccc(cc1)S(Cl)(=O)=O

InChI

1S/C7H7ClO2S/c1-6-2-4-7(5-3-6)11(8,9)10/h2-5H,1H3

InChI key

YYROPELSRYBVMQ-UHFFFAOYSA-N

Descrição geral

p-Toluenesulfonyl chloride is an organic sulfonyl chloride mainly used to convert hydroxyl groups into good leaving group by forming sulfonates.[1]

Aplicação

p-Toluenesulfonyl chloride may be used in the following processes:

In combination with N-methylimidazole for the esterification or thioesterification of carboxylic acids and alcohols or thiols.[2]

As an additive to enhance the yield of symmetrical biaryls via palladium chloride catalyzed homo-coupling of arylboronic acids in the absence of ligands.[3]

As a positive chlorine source for the ?-chlorination of ketones.[4]

Solvent-free tosylation of alcohols and phenols in the presence of heterodoxy acids.[5]

As an activator for reaction between 2-alkynylbenzaldoxime and phenols to form 1-aroxyisoquinolines in the presence of silver triflate.[6]

As a catalyst for the solvent-free preparation of symmetrical bis(benzhydryl)ethers from benzhydrols.[7]

Informações legais

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