P-Toluenesulfonyl Chloride Reagentplus® 99% - 500 Gr - Sigma
Código: 19851
P-Toluenesulfonyl Chloride ReagentPlus®, ≥99%
Sinônimo(s):
TsCl, Tosyl chloride
Fórmula linear:
CH3C6H4SO2Cl
Número CAS:
Peso molecular:
190.65
Beilstein:
607898
Número EC:
Número MDL:
ID de substância PubChem:
NACRES:
NA.21
pressão de vapor
1 mmHg ( 88 °C)
Nível de qualidade
linha de produto
ReagentPlus®
Ensaio
≥99%
forma
solid
pb
134 °C/10 mmHg (lit.)
pf
65-69 °C (lit.)
solubilidade
benzene: freely soluble(lit.)
chloroform: freely soluble(lit.)
ethanol: freely soluble(lit.)
water: insoluble(lit.)
SMILES string
Cc1ccc(cc1)S(Cl)(=O)=O
InChI
1S/C7H7ClO2S/c1-6-2-4-7(5-3-6)11(8,9)10/h2-5H,1H3
InChI key
YYROPELSRYBVMQ-UHFFFAOYSA-N
Descrição geral
p-Toluenesulfonyl chloride is an organic sulfonyl chloride mainly used to convert hydroxyl groups into good leaving group by forming sulfonates.[1]
Aplicação
p-Toluenesulfonyl chloride may be used in the following processes:
In combination with N-methylimidazole for the esterification or thioesterification of carboxylic acids and alcohols or thiols.[2]
As an additive to enhance the yield of symmetrical biaryls via palladium chloride catalyzed homo-coupling of arylboronic acids in the absence of ligands.[3]
As a positive chlorine source for the ?-chlorination of ketones.[4]
Solvent-free tosylation of alcohols and phenols in the presence of heterodoxy acids.[5]
As an activator for reaction between 2-alkynylbenzaldoxime and phenols to form 1-aroxyisoquinolines in the presence of silver triflate.[6]
As a catalyst for the solvent-free preparation of symmetrical bis(benzhydryl)ethers from benzhydrols.[7]
Informações legais
ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC