Z-Leu-Leu-Leu-Al 90% HPLC

Sinônimo(s):

MG-132

Empirical Formula (Hill Notation):

C₂₆H₄₁N₃O₅

Número CAS:

133407-82-6

Peso molecular:

475.62

Número MDL:

MFCD00674886

ID de substância PubChem:

24892475

NACRES:

NA.32

Nível de qualidade

200

Ensaio

≥90% (HPLC)

forma

powder

cor

white

solubilidade

DMSO: soluble

temperatura de armazenamento

−20°C

SMILES string

[H]C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1

InChI

1S/C26H41N3O5/c1-17(2)12-21(15-30)27-24(31)22(13-18(3)4)28-25(32)23(14-19(5)6)29-26(33)34-16-20-10-8-7-9-11-20/h7-11,15,17-19,21-23H,12-14,16H2,1-6H3,(H,27,31)(H,28,32)(H,29,33)/t21-,22-,23-/m0/s1

InChI key

TZYWCYJVHRLUCT-VABKMULXSA-N

Gene Information

human ... CTSB(1508) , NFKB1(4790) , PSMA1(5682)

Amino Acid Sequence

Z-Leu-Leu-Leu-al

Aplicação

Z-Leu-Leu-Leu-al or MG132 has been used as a proteasome inhibitor.[1][2] It has also been used to test the ubiquitylation and sumoylation pathways in urchin embryos.[3]