Isoquercitrin Primary Reference Standard

Sinônimo(s):

Quercetin 3-β-D-glucoside, 3,3′,4′,5,7-Pentahydroxyflavone 3-β-glucoside, Isoquercitrin

Fórmula empírica (Notação de Hill):

C₂₁H₂₀O₁₂

Número CAS:

482-35-9

Peso molecular:

464.38

Beilstein:

100989

Número MDL:

MFCD00017746

ID de substância PubChem:

329747007

NACRES:

NA.24

grau

primary reference standard

prazo de validade

limited shelf life, expiry date on the label

fabricante/nome comercial

HWI

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

cadeia de caracteres SMILES

OC[C@H]1O[C@@H](OC2=C(Oc3cc(O)cc(O)c3C2=O)c4ccc(O)c(O)c4)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C21H20O12/c22-6-13-15(27)17(29)18(30)21(32-13)33-20-16(28)14-11(26)4-8(23)5-12(14)31-19(20)7-1-2-9(24)10(25)3-7/h1-5,13,15,17-18,21-27,29-30H,6H2/t13-,15-,17+,18-,21+/m1/s1

chave InChI

OVSQVDMCBVZWGM-QSOFNFLRSA-N

Descrição geral

Isoquercitrin is a flavonoid, glucoside derivative of quercitrin, and protein disulfide isomerase (PDI) inhibitor. Obtained from the leaf of medicinal plants, such as Apocynum venetum among others, it is known for its anti-oxidant and anti-thrombotic activities.

Produced and qualified by HWI pharma services GmbH.
Exact content measured by quantitative NMR can be found on the certificate.

Aplicação

The primary reference standard can be used for identification, assay, and purity testing, method development, and validation.It can also be used as follows:

• Development of a synergistic cloud point extraction (SCPE) method for the extraction of isoquercitrin in rat plasma samples and its subsequent analysis by high-performance liquid chromatography (HPLC)

• Electrochemical analysis of isoquercitrin and epigallocatechin gallate by cyclic voltammetry using carbon nanotubes based electrode

• Simultaneous determination of rutin and isoquercitrin by differential pulse voltammetry (DPV) using glassy carbon electrode (GCE) modified with deposition of thio-β-cyclodextrin functionalized graphene/palladium nanoparticles (SH-β-CD-Gr/PdNPs) for pharmaceutical and medical analysis

• Multi-residue analysis of isoquercitrin, campesterol, emodin 8-O-β-D-glucopyranoside, and quercetin in dried stem and flower extracts of Reynoutria sachalinensis by high-performance liquid chromatography coupled with diode-array detection