Nourseothricin Sulfate Suitable For Cell Culture - 10 Mg - Sigma
Código: 21330
Nourseothricin Sulfate Suitable For Cell Culture
Sinônimo(s):
ClonNAT, NTC
fonte biológica
Streptomyces sp.
Nível de qualidade
forma
powder
temperatura de armazenamento
2-8°C
Descrição geral
Chemical structure: peptidyl nucleoside, aminoglycoside antibiotic. Nourseothricin (NTC) is a mixture of the related compounds streptothricin C, D, E, and F.
Aplicação
Nourseothricin is used as a dominant selection antibiotic for genetically modified bacteria, yeasts, fungi, protozoa and plants.
Ações bioquímicas/fisiológicas
Nourseothricin inhibits biosynthesis and induces miscoding. Resistance to nourseothricin is mediated by the sat1 encoded N-acetyltransferase. Nourseothricin is inactivated by acetylation of the β-amino group of the β-lysin.
Antifungal effective against Candida albicans. Candida species transformed with the gene encoding nourseothricin acetyltransferase (CaNAT1) were resistant to nourseothricin.
Outras notas
Keep container tightly closed in a dry and well-ventilated place.