Nourseothricin Sulfate Suitable For Cell Culture

Sinônimo(s):

ClonNAT, NTC

fonte biológica

Streptomyces sp.

Nível de qualidade

200

forma

powder

temperatura de armazenamento

2-8°C

Descrição geral

Chemical structure: peptidyl nucleoside, aminoglycoside antibiotic. Nourseothricin (NTC) is a mixture of the related compounds streptothricin C, D, E, and F.

Aplicação

Nourseothricin is used as a dominant selection antibiotic for genetically modified bacteria, yeasts, fungi, protozoa and plants.

Ações bioquímicas/fisiológicas

Nourseothricin inhibits biosynthesis and induces miscoding. Resistance to nourseothricin is mediated by the sat1 encoded N-acetyltransferase. Nourseothricin is inactivated by acetylation of the β-amino group of the β-lysin.

Antifungal effective against Candida albicans. Candida species transformed with the gene encoding nourseothricin acetyltransferase (CaNAT1) were resistant to nourseothricin.

Outras notas

Keep container tightly closed in a dry and well-ventilated place.