β-Carotene

synthetic, ≥93% (UV), powder

Sinônimo(s):

β,β-Carotene, Provitamin A

Empirical Formula (Hill Notation):

C₄₀H₅₆

Número CAS:

7235-40-7

Peso molecular:

536.87

Beilstein:

1917416

Número EC:

230-636-6

Número MDL:

MFCD00001556

ID de substância PubChem:

24893189

NACRES:

NA.79

fonte biológica

synthetic

Nível de qualidade

200

Ensaio

≥93% (UV)

forma

powder

potência

~1,600,000 units vitamin A per g

cor

dark red to brown

pf

178-179 °C

solubilidade

hexane: 1.1 mg/mL
DMSO: 30 μg/mL

temperatura de armazenamento

2-8°C

SMILES string

CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C2=C(C)CCCC2(C)C)C(C)(C)CCC1

InChI

1S/C40H56/c1-31(19-13-21-33(3)25-27-37-35(5)23-15-29-39(37,7)8)17-11-12-18-32(2)20-14-22-34(4)26-28-38-36(6)24-16-30-40(38,9)10/h11-14,17-22,25-28H,15-16,23-24,29-30H2,1-10H3/b12-11+,19-13+,20-14+,27-25+,28-26+,31-17+,32-18+,33-21+,34-22+

InChI key

OENHQHLEOONYIE-JLTXGRSLSA-N

Descrição geral

Carotenoids are an important class of naturally occurring pigments found in fruits and vegetables. Among the carotenoids, β-carotene has the greatest provitamin A potential and functions to reduce the risk of cancer, cardiovascular diseases and macular degeneration. Low water solubility and poor chemical stability attributes to low absorption of β-carotene from food. β-carotene along with digestible lipids enriches its bio accessibility. Emulsions or nano emulsions encapsulates effectively delivers lipophilic β-carotene and increases its bioavailability.[1] β-carotene has anti-oxidant potential and reduces noise induced hearing loss and progression of macular degeneration.[2]

Aplicação

β-carotene has been used:

to generate nano emulsions to evaluate their bioavailability potential[1]

as a standard, for β-carotene evaluation in blood and skin samples using high performance liquid chromatography (HPLC),[3]

as a dietary supplement of vitamin-A in young rats by HPLC[4]

as a dietary supplement in mice to reduce hearing loss and hair cell damage[2]

Ações bioquímicas/fisiológicas

The most important of the provitamins A, β-carotene can be classified as an antioxidant due to its inhibition of radical initiated peroxidation in vitro. However, in vivo it appears to act either as an antioxidant or a prooxidant depending on cellular environment. It reduces the incidence of many cancers, but enhances lung cancer incidence in smokers.

Embalagem

Packaged in serum vials.