all trans-Retinal powder, ≥98%

Sinônimo(s):

Vitamin A aldehyde

About This Item

Fórmula empírica (Notação de Hill):

C₂₀H₂₈O

Número CAS:

116-31-4

Peso molecular:

284.44

Número MDL:

MFCD00001550

Código UNSPSC:

12352205

ID de substância PubChem:

24899355

NACRES:

NA.79

fonte biológica

synthetic (organic)

Nível de qualidade

200

Ensaio

≥98%

Formulário

powder

técnica(s)

HPLC: suitable

cor

yellow

pf

62-64 °C

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

[H]C(=O)\C=C(C)\C=C\C=C(C)\C=C\C1=C(C)CCCC1(C)C

InChI

1S/C20H28O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,15H,7,10,14H2,1-5H3/b9-6+,12-11+,16-8+,17-13+

chave InChI

NCYCYZXNIZJOKI-OVSJKPMPSA-N

Descrição geral

All trans-Retinal is one of the major derivatives of vitamin A group. A variety of food serves as a source of vitamin A. It is predominant in liver and among the brightly colored vegetables.[1]

Aplicação

All trans-Retinal has been used:

• in optogenetic experiments[2]

• in electrophysiological experiment[3]

• to study the effect of AKR1B10 (aldo-keto reductase (AKR) superfamily member) on the conversion of retinal to retinol in the airway epithelium[4]

• in decidual transformation of human endometrial stromal cells[5]

Ações bioquímicas/fisiológicas

All-trans retinal is converted to retinoic acid in vivo by the action of retinal dehydrogenase. Retinoic acid is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR) that act as transcription factors to regulate the growth and differentiation of normal and malignant cells. Retinal isomers are also chromophores that bind to opsins, a family of G-protein-linked transmembrane proteins, to form photosensitive receptors in visual and nonvisual systems. All-trans retinal is a potent photosensitizer.

Embalagem

Sealed ampule.