Norfloxacin analytical standard, ≥98% (TLC)

Sinônimo(s):

1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid, 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazino-3-quinolinecarboxylic acid

About This Item

Fórmula empírica (Notação de Hill):

C₁₆H₁₈FN₃O₃

Número CAS:

70458-96-7

Peso molecular:

319.33

Número CE:

274-614-4

Número MDL:

MFCD00079532

Código UNSPSC:

41116107

ID de substância PubChem:

329818696

NACRES:

NA.24

grau

analytical standard

Nível de qualidade

200

Agency

EPA 1694

Ensaio

≥98% (TLC)

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

aplicação(ões)

clinical testing

Formato

neat

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

CCN1C=C(C(O)=O)C(=O)c2cc(F)c(cc12)N3CCNCC3

InChI

1S/C16H18FN3O3/c1-2-19-9-11(16(22)23)15(21)10-7-12(17)14(8-13(10)19)20-5-3-18-4-6-20/h7-9,18H,2-6H2,1H3,(H,22,23)

chave InChI

OGJPXUAPXNRGGI-UHFFFAOYSA-N

Informações sobre genes

human ... CYP1A2(1544)
rat ... Gabra1(29705)

Descrição geral

Chemical structure: fluoroquinolone

Norfloxacin is a broad spectrum antibiotic, which is used against a wide variety of gram positive and gram negative bacteria.[1]

Aplicação

Norfloxacin may be used as a standard in the determination of norfloxacin in human serum samples using fluorometric spectrophotometry.[1]

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Ações bioquímicas/fisiológicas

Norfloxacin blocks DNA replication by interfering with an ATP-induced structural transition of DNA complexed with DNA gyrase (topoisomerase).
Mode of action: inhibits bacterial DNA replication
Antimicrobial spectrum: Gram-negative bacteria; less effective against Gram-positive bacteria