Enrofloxacin ≥99.0%

Sinônimo(s):

Baytril

About This Item

Fórmula empírica (Notação de Hill):

C₁₉H₂₂FN₃O₃

Número CAS:

93106-60-6

Peso molecular:

359.39

Beilstein:

5307824

Número MDL:

MFCD00792463

Código UNSPSC:

41116105

ID de substância PubChem:

329751571

NACRES:

NA.21

Nível de qualidade

200

Ensaio

≥99.0%
99.0-101.0% (dried substance)

Formulário

powder or crystals

espectro de atividade do antibiótico

Gram-negative bacteria
Gram-positive bacteria

Modo de ação

DNA synthesis | interferes
enzyme | inhibits

cadeia de caracteres SMILES

CCN1CCN(CC1)c2cc3N(C=C(C(O)=O)C(=O)c3cc2F)C4CC4

InChI

1S/C19H22FN3O3/c1-2-21-5-7-22(8-6-21)17-10-16-13(9-15(17)20)18(24)14(19(25)26)11-23(16)12-3-4-12/h9-12H,2-8H2,1H3,(H,25,26)

chave InChI

SPFYMRJSYKOXGV-UHFFFAOYSA-N

Descrição geral

Chemical structure: fluoroquinolone

Enrofloxacin is a veterinary fluoroquinolone (FQ) antibiotic with broad-spectrum antimicrobial activity. FQ drugs chelate to iron with high affinity. This chelation leads to inhibition of Fe(II)-dependent dioxygenases involved in the regulation of epigenetic control, collagen maturation, and HIF (hypoxia-inducible factor) degradation. The side effects associated with FQ drugs are renal toxicity and tendinopathy. Enrofloxacin is used in aquaculture and its use may cause an increase in the growth of antibiotic resistant microbes in an aquatic environment. The drug may have negative effects on public health and environment.[1][2][3]

Aplicação

Enrofloxacin has been used:

• to investigate the pathological mechanisms resulting from the toxicity of fluoroquinolones in mammalian cells[1]

• to prepare a standard solution with 50% acetonitrile in a study to analyze illegal fish drugs used in aquaculture by employing surface-enhanced Raman spectroscopy (SERS)[2]

• as an analyte in a chemiluminescence reagent system[4]