Ciprofloxacin ≥98% (HPLC)

Sinônimo(s):

1-Cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid, Ciprobay

About This Item

Fórmula empírica (Notação de Hill):

C₁₇H₁₈FN₃O₃

Número CAS:

85721-33-1

Peso molecular:

331.34

Beilstein:

3568352

Número MDL:

MFCD00185755

Código UNSPSC:

41116105

ID de substância PubChem:

329751572

NACRES:

NA.21

Agency

EPA 1694

Nível de qualidade

200

Ensaio

≥98% (HPLC)

Formulário

powder or crystals

espectro de atividade do antibiótico

Gram-negative bacteria
Gram-positive bacteria

aplicação(ões)

environmental

Modo de ação

DNA synthesis | interferes
enzyme | inhibits

cadeia de caracteres SMILES

OC(=O)C1=CN(C2CC2)c3cc(N4CCNCC4)c(F)cc3C1=O

InChI

1S/C17H18FN3O3/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24/h7-10,19H,1-6H2,(H,23,24)

chave InChI

MYSWGUAQZAJSOK-UHFFFAOYSA-N

Informações sobre genes

human ... CYP1A2(1544) , KCNH1(3756)
rat ... Gabra1(29705)

Descrição geral

Ciprofloxacin is a second-generation broad-spectrum fluoroquinolone antibiotic with extensive antimicrobial and pharmacokinetic properties that is widely used to combat bacterial infections. Its chemical name is 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid.[1][2]

Chemical structure: fluoroquinolone

Aplicação

Ciprofloxacin is widely used in clinical practices against Gram-positive and Gram-negative bacteria and the treatment of a broad range of infections, including those of the skin, eyes, urinary tract, lower respiratory tract, gastrointestinal tract, et cetera. It can also be combined with various antimicrobial agents to combat bacterial biofilms as well as multidrug-resistant microorganisms.[1] Its derivatives have been developed to synthesize novel antibacterials with enhanced potency and diverse antimicrobial effects including antibacterial, antifungal, anti-HIV, anti-tumor, and anti-TB properties.[2]

Ações bioquímicas/fisiológicas

The mechanism of action of Ciprofloxacin is the inhibition of bacterial DNA synthesis by blocking the subunit A of DNA gyrase enzyme as well as by affecting the bacterial cell wall.[1]