(−)-Epicatechin 98% (HPLC)  ≥98% (HPLC), from green tea

Sinônimo(s):

(−)-cis-3,3′,4′,5,7-Pentahydroxyflavane, (2R,3R)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol

About This Item

Fórmula empírica (Notação de Hill):

C₁₅H₁₄O₆

Número CAS:

490-46-0

Peso molecular:

290.27

Beilstein:

92760

Número CE:

207-710-1

Número MDL:

MFCD00075648

Código UNSPSC:

12352205

ID de substância PubChem:

24894538

NACRES:

NA.77

fonte biológica

green tea

Nível de qualidade

200

Ensaio

≥98% (HPLC)

pf

240 °C (dec.) (lit.)

aplicação(ões)

metabolomics
vitamins, nutraceuticals, and natural products

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3ccc(O)c(O)c3

InChI

1S/C15H14O6/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7/h1-5,13,15-20H,6H2/t13-,15-/m1/s1

chave InChI

PFTAWBLQPZVEMU-UKRRQHHQSA-N

Informações sobre genes

human ... BACE1(23621), CYP1A2(1544)

Descrição geral

Epicatechin is a flavanol, that belongs to the class of secondary, polyphenolic plant metabolites.[1]

Aplicação

(-)-Epicatechin has been used:

• to examine its biological effects in cell lines from human gender-specific cancers[2]

• to study its antiviral activity[3]

• to test its ability to regenerate this enzymatic activity both in vitro at the isolated MPO−H₂O₂−Cl- system and ex vivo in human polymorphonuclear leukocytes (PMNs)[4]

Ações bioquímicas/fisiológicas

This antioxidant is found in chocolate. (-)-Epicatechin is linked with cardiovascular effects. It is considered as a dependable standard due to its availability in cacao seeds and cocoa products.[5] The halogenating activity of myeloperoxidase can be restored by (-)-epicatechin.[4]