2,2,2-Trifluoroethanol ReagentPlus^®, ≥99%

Sinônimo(s):

Trifluoroethyl alcohol

About This Item

Fórmula linear:

CF₃CH₂OH

CAS Number:

75-89-8

Peso molecular:

100.04

Beilstein:

1733203

Número CE:

200-913-6

Número MDL:

MFCD00004672

Código UNSPSC:

12191601

ID de substância PubChem:

329826635

NACRES:

NA.21

densidade de vapor

3.5 (vs air)

pressão de vapor

70 mmHg ( 25 °C)

linha de produto

ReagentPlus^®

Ensaio

≥99%

Formulário

liquid

temperatura de autoignição

~896 °F

Lim. expl.

42 %

dilution

(for general lab use)

índice de refração

n20/D 1.3 (lit.)

pH

7

p.e.

77-80 °C (lit.)

pf

−44 °C (lit.)

densidade

1.373 g/mL at 25 °C (lit.)

cadeia de caracteres SMILES

OCC(F)(F)F

InChI

1S/C2H3F3O/c3-2(4,5)1-6/h6H,1H2

chave InChI

RHQDFWAXVIIEBN-UHFFFAOYSA-N

Descrição geral

2,2,2-Trifluoroethanol (TFE) is an organic compound with the chemical formula CF₃CH₂OH. TFE is a commonly used solvent in organic synthesis. It can also be used as a cosolvent in the experimental study of proteins and peptides.

Aplicação

2,2,2-Trifluoroethanol can be used as a solvent:

In the synthesis of 2-amino-3-cyano-4H-chromene and tetrahydrobenzo[b]pyran derivatives by catalyst free one-pot condensation of aldehydes, malononitrile and resorcinol or dimedone.

In the N-formylation of amines with formic acid in the presence of heterogeneous ZIF-8 (zeolitic imidazolate framework) catalyst.

In the preparation of 2-substituted-2,3-dihydro-4(1H)-quinazolinone derivatives by condensation of anthranilamide with alkyl, aryl, or heteroaryl ketones or aldehydes.

In the mild and selective oxidation of sulfur compounds using H₂O₂(hydrogen peroxide).

Características e benefícios

2,2,2-Trifluoroethanol is more acidic than ethanol due to the presence of electronegative trifluoromethyl group.

Informações legais

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany