Ácido (±)-abscísico synthetic, 98%

Sinônimo(s):

ABA, Dormina, Ácido (2Z,4E)-5-(1-hidroxi-2,6,6-trimetil-4-oxo-2-cicloexeno-1-il)-3-metil-2,4-pentadienoico

Sobre este item

Fórmula empírica (Notação de Hill):

C₁₅H₂₀O₄

Número CAS:

14375-45-2

Peso molecular:

264.32

Número MDL:

MFCD00075619

Código UNSPSC:

12352100

ID de substância PubChem:

24888569

NACRES:

NA.22

Nível de qualidade

100

Ensaio

98%

Formulário

powder

pf

186-188 °C (lit.)

grupo funcional

carboxylic acid
hydroxyl
ketone

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

CC(\C=C\C1(O)C(C)=CC(=O)CC1(C)C)=C\C(O)=O

InChI

1S/C15H20O4/c1-10(7-13(17)18)5-6-15(19)11(2)8-12(16)9-14(15,3)4/h5-8,19H,9H2,1-4H3,(H,17,18)/b6-5+,10-7-

chave InChI

JLIDBLDQVAYHNE-LXGGSRJLSA-N

Descrição geral

2-cis,4-trans-Abscisic acid (ABA) is an organic compound used as a starting material in in organic synthesis. It is also used as a chiral auxiliary during asymmetric synthesis. ABA derivatives can be used to control the stereochemistry of reactions by serving as chiral templates that induce the formation of specific products. [1]

Aplicação

• Chiral Separation of Abscisic Acid: Research demonstrated direct chiral separation of abscisic acid using high-performance liquid chromatography with a phenyl column and a gamma-cyclodextrin mobile phase, advancing the analytical methods essential for studying plant stress hormones (Terashima et al., 2023).

• Xanthine Oxidase Inhibitory Activity: A study including abscisic acid derivatives showed significant xanthine oxidase inhibitory activity, offering potential health benefits and therapeutic applications (Miyata et al., 2019).

• Anticancer Potential: Extracts containing abscisic acid from mangrove endophytic fungi exhibited cytotoxic properties and induced G(0)/G(1) cell cycle arrest and apoptosis in human cancer cells, highlighting their potential in cancer treatment strategies (Zhou et al., 2018).

• Antidiabetic Activity: Extracts involving abscisic acid from an endophytic fungus showed promising antidiabetic activity, potentially improving treatment options for diabetes through natural product research (Uzor et al., 2017).

• Glucose Tolerance and Insulinemia Reduction: A groundbreaking study found that microgram amounts of abscisic acid in fruit extracts significantly improve glucose tolerance and reduce insulin levels in rats and humans, suggesting its use as a dietary supplement for managing diabetes (Magnone et al., 2015).