Tiamina reagent grade, ≥99% (HPLC)

Sinônimo(s):

Aneurina, Vitamina B₁

Sobre este item

Fórmula empírica (Notação de Hill):

C₁₂H₁₇ClN₄OS · HCl

Número CAS:

67-03-8

Peso molecular:

337.27

Beilstein:

3851771

Número CE:

200-641-8

Número MDL:

MFCD00012780

Código UNSPSC:

12352209

eCl@ss:

34058006

ID de substância PubChem:

24900057

NACRES:

NA.26

fonte biológica

synthetic (organic)

Nível de qualidade

200

grau

reagent grade

Ensaio

≥99% (HPLC)

Formulário

powder

técnica(s)

HPLC: suitable

cor

white

pf

250 °C (dec.) (lit.)

solubilidade

H₂O: 50 mg/mL, clear, colorless

cadeia de caracteres SMILES

CC1=NC(N)=C(C[N+]2=CSC(CCO)=C2C)C=N1.Cl.[Cl-]

InChI

1S/C12H17N4OS.2ClH/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13;;/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15);2*1H/q+1;;/p-1

chave InChI

DPJRMOMPQZCRJU-UHFFFAOYSA-M

Descrição geral

Thiamine is a water-soluble vitamin-B complex. Structurally, it possesses a five-membered thiazolium ring and a six-membered amino-pyrimidine ring connected by a methyl group. Thiamine is naturally available in fruits, vegetables, poultry, eggs.[1]

Aplicação

Thiamine hydrochloride has been used as a vitamin supplement to the holidic medium[2] and in bacterial growth medium.[3][4]

Ações bioquímicas/fisiológicas

Thiamine is an essential coenzyme in carbohydrate metabolism.[5] Deficiency of thiamine causes beriberi, a neurological and cardiovascular disease.[1] Thiamine is administered in case of deficiency, either due to reduced intake or synthesis.[5][1] Congenital defect in the thiamine transporter gene SLC19A2 causes thiamine-responsive megaloblastic anemia syndrome (TRMA). Thiamine mimics acetylcholine in brain and possible exerts a role in Alzheimer′s disease.[1] Thiamine deficiency in ruminants causes polioencephalomalacia.[5]