6-Biopterin

≥97%

Sinônimo(s):

(1’R,2’S)-Biopterin, 2-Amino-4-hydroxy-6-(1,2-dihydroxypropyl)pteridine, L-erythro-6-(1,2-Dihydroxypropyl)pterin

Sobre este item

Fórmula empírica (Notação de Hill):

C₉H₁₁N₅O₃

Número CAS:

22150-76-1

Peso molecular:

237.22

UNSPSC Code:

41106305

NACRES:

NA.51

PubChem Substance ID:

24891654

EC Number:

244-807-8

Beilstein/REAXYS Number:

87860

MDL number:

MFCD00036787

Form:

powder

Assay:

≥97%

Solubility:

1 M NaOH: soluble-10 mg/mL, clear, colorless to light greenish-yellow

Biological source:

synthetic

Propriedades

biological source

synthetic

Quality Level

200

assay

≥97%

form

powder

solubility

1 M NaOH: soluble-10 mg/mL, clear, colorless to light greenish-yellow

storage temp.

2-8°C

SMILES string

C[C@H](O)[C@H](O)c1cnc2NC(N)=NC(=O)c2n1

InChI

1S/C9H11N5O3/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7/h2-3,6,15-16H,1H3,(H3,10,11,13,14,17)/t3-,6-/m0/s1

InChI key

LHQIJBMDNUYRAM-DZSWIPIPSA-N

Descrição

Application

6-Biopterin is an oxidation product from the melanogenesis regulating cofactor (6R)5,6,7,8 tetrahydrobiopterin (6-BH4). In vitro, 6-Biopterin is cytotoxic to melanocytes. However, in vivo, 6-Biopterin is rapidly and sequentially reduced back to 6-GH4 via q-BH2. Recent studies suggest that 6-Biopterin among other pteridines may be a useful non-invasive biomarker for cancer.