Histamine Dihydrochloride 99% (Tlc) - 5 Gr - Sigma
Código: 26060
Histamine dihydrochloride
≥99% (TLC), powder, endogenous histamine receptor agonist
Sinônimo(s):
2-(4-Imidazolyl)ethylamine dihydrochloride
Sobre este item
Fórmula empírica (Notação de Hill):
C5H9N3 · 2HCl
Número CAS:
Peso molecular:
184.07
NACRES:
NA.77
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352116
EC Number:
200-298-4
MDL number:
Beilstein/REAXYS Number:
3624116
Assay:
≥99% (TLC)
Form:
powder
Quality level:
Propriedades
Nome do produto
Histamine dihydrochloride, ≥99% (TLC), powder
Quality Level
assay
≥99% (TLC)
form
powder
color
white to off-white
mp
249-252 °C (lit.)
storage temp.
2-8°C
SMILES string
Cl[H].Cl[H].NCCc1c[nH]cn1
InChI
1S/C5H9N3.2ClH/c6-2-1-5-3-7-4-8-5;;/h3-4H,1-2,6H2,(H,7,8);2*1H
InChI key
PPZMYIBUHIPZOS-UHFFFAOYSA-N
Gene Information
human ... HRH1(3269), HRH2(3274)
Descrição
General description
Histamine dihydrochloride is a derivative of histamine. It prevents the formation of ROS (reactive oxygen species), which inhibits the activation of T cells and natural killer cells. Histamine dihydrochloride is implicated in tumor cell apoptosis. It prevents the relapse of acute myeloid leukemia in patients.
Application
Histamine dihydrochloride has been used:
-
as a orthograde cotransmitter in producing excitatory postsynaptic potential (EPSP)
-
to determine its level in fish using HPLC (high performance liquid chromatography)
-
to assess the tracheal response to antigens in guinea-pigs
Biochem/physiol Actions
Endogenous H1 and H2 histamine receptor agonist; activates nitric oxide synthetase; potent vasodilator.
Features and Benefits
This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
